Yes and no. If you just pick up a normal Z28/Formula/TransAm, I'm not aware of any changes besides maybe springs for the weight differences.
However the WS6 and SS have better shocks, thicker swaybars (IIRC), and slightly better springs.
Not worth enough to justify buying an SS or WS6 over any other LS1 fbody. Most people that modify their cars will be better setup than the stock form anyway.
I ran Eibach Pro-Kit, with BMR adjustible Panhard Rod, and lower trailing arms on mine and it'd hug the road pretty good. But I was also running a 275 tire up front and 315's out back.
Here was mine,